I
recently completed the Ph.D. program in Pharmacology and
Toxicology and currently work as a Research Associate on
Alzheimer's disease projects.
My dissertation/thesis
focused on hydrazine hepatotoxicity, a common manifestation
of isoniazed therapy. A pathological
hallmark of hydrazine hepatotoxicity in rodents is fatty
liver (steatosis). The project has been successful in clarifying
mechanisms involved in hepatic lipid accumulation including
the involvement of PPARalpha, a novel mechanism. |