Contributions to the Research & Society
The studies of
ovarian toxicity are relevant to the ability of environmental
chemicals to cause an early onset of menopause
in women. This is important because menopause is known to
be associated with increased risks for a number of disorders
such as cardiovascular disease, osteoporosis, Alzheimer’s
disease, and depression. Thus, undergoing early menopause
would expose a woman to more years with these increased health
risks. The mouse model for menopause will be useful to researchers
studying menopause-associated diseases as well as to pharmaceutical
companies developing ideal formulations of drugs for treatment
of menopause-associated conditions or for hormone replacement
therapy.
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